WebDec 3, 2024 · While in Fig 1 an increase in cytotoxicity (i.e. loss of membrane integrity) was observed in HT-29 cells treated with holamine (15 ug/ml), MCF-7 and HeLa cells treated with holamine and funtumine (15 ug/ml), this is not the case in Fig 2 for the 10 ug/ml, where also a loss of membrane integrity is measured, although with a different method. Fig 2. WebThe * indicates statistical significance at p < 0.05 among the cell lines for each concentration-i.e., for the apoptosis result in Panel A, the effect elicited by 7.5 µg/mL of …

Holarrhena pubescens - Useful Tropical Plants

WebHolamine and funtumine cytotoxicity and cell cycle arrest had been previously reported. The present study evaluates the apoptotic effects, reactive oxygen species (ROS) induction, … WebMoreover, steroidal alkaloids including hookerianamide-1, hookerianamide-H, hookerianamide-J, hookerianamide-K, dehydrosarsalignone, vagenine-A, sarcovagine-C, holaphylline, saracodine, holamine, 15-α hydroxyholamine, holacurtin, N-desmethyl holacurtine and elasticine has exhibited time and dose-dependent efficacy against … professionalism why it\u0027s important

Holamine C21H33NO - PubChem

WebHolamine and funtumine, steroidal alkaloids with strong and diverse pharmacological activities are commonly found in the Apocynaceae family of Holarrhena. The selective anti-proliferative and cell ... WebHolamine and funtumine, steroidal alkaloids with strong and diverse pharmacological activities are commonly found in the Apocynaceae family of Holarrhena. The selective anti-proliferative and cell ... Webholamine Adrenal medulla Stress (adrenalin) Ner vous system Low blood glucose Glucocorticoids Steroid hormone Adrenal cortex Stress Low blood glucose Glucagon is the most important hormone signaling low blood glucose concentration, while epinephrine and glucocorticoids play secondary roles. 31 Regulation of glycogen metabolism professionalism towards suppliers