Ctgf wikipedia
WebCTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN intercellular signaling protein). CTGF has important roles in many biological processes, including cell adhesion, migration, proliferation, angiogenesis, skeletal development, and … CTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN intercellular signaling protein). CTGF has important roles in many biological processes, including cell adhesion, migration, … See more Members of the CCN protein family, including CTGF, are structurally characterized by having four conserved, cysteine-rich domains. These domains are, from N- to C-termini, the insulin-like growth factor … See more Knockout mice with the Ctgf gene disrupted die at birth due to respiratory stress as a result of severe chondrodysplasia. Ctgf-null mice also show defects in angiogenesis, with impaired interaction between endothelial cells and pericytes … See more • Human CTGF genome location and CTGF gene details page in the UCSC Genome Browser. See more CTGF is associated with wound healing and virtually all fibrotic pathology. It is thought that CTGF can cooperate with TGF-β to … See more • Ctgf/hcs24 CAESAR • CYR61 (CCN1) See more
Ctgf wikipedia
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WebConnective tissue growth factor (CTGF), also termed fisp12, βIG-M2, and IGF-BP8, is a secreted cysteine-rich growth factor that belongs to the CCN (cyr61, CTGF, nov) family. … WebOct 26, 2024 · Idiopathic pulmonary fibrosis (IPF) is a type of chronic lung disease that causes progressively worsening dyspnea (shortness of breath). People with IPF may also experience a dry and persistent cough, progressive fatigue, or unexplained weight loss.
WebConnective tissue growth factor (CTGF) is a member of the recently described CCN gene family which contains CTGF itself, cyr61, nov, elm1, Cop1, and WISP-3. CTGF is transcriptionally activated by several factors although its stimulation by transforming growth factor beta (TGF-beta) has attracted considerable attention. WebCTGF, also known as CCN2 or connective tissue growth factor,[5][6] is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins …
WebMar 10, 2024 · Connective tissue growth factor (CTGF), also known as CCN2, is a member of the CCN protein family of secreted proteins with roles in diverse biological processes. WebJun 6, 2012 · Key roles for connective tissue growth factor (CTGF/CCN2) are demonstrated in the wound repair process where it promotes myofibroblast differentiation and angiogenesis. Similar mechanisms are active in tumor-reactive stroma where CTGF is expressed. Other potential roles include prevention of hypoxia-induced apoptosis and …
WebJun 26, 2024 · Connective tissue growth factor (CTGF) or cellular communication network 2 (CCN2) is a matricellular protein essential for normal embryonic development and tissue repair. CTGF exhibits cell- and context-dependent activities, but CTGF function in vascular development and barrier function is unknown. We show that endothelial cells (ECs) are …
WebConnective tissue growth factor: a fibrogenic master switch in fibrotic liver diseases. Liver Int. 2008 Sep;28 (8):1065-79; Gygi D, Zumstein P, Grossenbacher D, Altwegg L, Luscher TF, Gehring H. Human connective tissue growth factor expressed in Escherichia coli is a non-mitogenic inhibitor of apoptosis. Biochem Biophys Res Commun. 2003 Nov 21 ... regent multiplex ballarat gold classWebFeb 1, 2011 · Connective tissue growth factor (CTGF) is widely thought to promote the development of fibrosis in collaboration with transforming growth factor (TGF)-β; however, most of the evidence for its involvement comes from correlative and culture-based studies. In this study, the importance of CTGF in tissue fibrosis was directly examined in three … problem of flightsWebNational Center for Biotechnology Information regent multiplex ballarat session timesWebConnective tissue growth factor, also known as CCN2, is a cysteine-rich matricellular protein involved in the control of biological processes, such as cell proliferation, differentiation, … regent movie theatreWebJun 28, 2024 · CTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrixassociated heparinbinding proteins (see also CCN intercellular signaling protein). CTGF has important roles in many biological processes, including cell adhesion, migrat problem of floodingWebCritical Transfer Frames. CTF. Currency Transaction File. CTF. Court Technology Forum. CTF. California Treatment Facility (Soledad, CA) showing only Military and Government … regent musicctgf/hcs24 CAESAR is the name given to the cis-acting RNA element identified in the 3' untranslated region (3'UTR) of the human connective tissue growth factor (CTGF) messenger RNA. This gene is also known as hypertrophic chondrocyte specific 24 (hcs24). The importance of the 3'UTR in repressing ctgf gene expression was initially c… problem officer meme